Brucella treatment in child

Depending on the timing of treatment and severity of illness, recovery may take a few weeks to several months. Death from brucellosis is rare, occurring in no more than 2% of all cases. Generally, the antibiotics doxycycline and rifampin are recommended in combination for a minimum of 6-8 weeks. Let your doctor know if you are There is a limited number of antibiotics that can be used for the treatment of brucella infections including doxycycline, rifampicin, trimethoprime-sulfamethoxazole, streptomycin, gentamicin and ciprofloxacin (see Table 1). . A common combination for children yielding successful results is as follows In children under 8 years old, the preferred regimen is rifampin with cotrimoxazole or gentamicin. Rifampin (900 mg once daily for 6 weeks) is considered the drug of choice for treating brucellosis in pregnant women Approach Considerations The goal of medical therapy in brucellosis is to control symptoms as quickly as possible in order to prevent complications and relapses. Initial care for brucellosis is.. - Brucellosis is a zoonosis that mainly affects livestock animals. (5 to 15% of cases, even months after end of initial treatment) or the infection may become chronic. Children 8 years and over. doxycycline + rifampicin or doxycycline + gentamicin. Adults

Treatment Brucellosis CD

Treatment recommendations for children consist of combination therapy with a tetracycline (for children ≥8 years) or trimethoprim-sulfamethoxazole (TMP-SMX, for children <8 years) and at least one other drug including rifampin, gentamicin, or streptomycin, depending upon the site of infection.[7,8,9 Treatment of brucellosis requires administration of effective antibiotics for an adequate length of time (Alshaalan et al., 2014). Several serological studies have shown that brucellosis is.

Signs and symptoms of brucellosis may include fever, joint pain and fatigue. The infection can usually be treated with antibiotics. However, treatment takes several weeks to months, and the infection can recur. Brucellosis affects hundreds of thousands of people and animals worldwide The most common antibiotics used were cotrimoxazole plus gentamycin in 83 cases (47.5%) and cotrimoxazole plus rifampin in 72 cases (41%). Conclusions: Brucellosis presents in various ways and should be differentiated from arthritis in countries where Brucella is endemic Children, pregnant women, immunosuppressed individuals, and those with artificial heart valves may be at increased risk of infection. Treatment Brucellosis is considered a lifelong infection in dogs. Treatment of infected animals consists of surgical sterilization and long-term antimicrobial drugs. Treatment usually consists of a combination o Treatment of brucellosis in children with antibiotics is supplemented with vaccine therapy. The killed brucellosis vaccine is administered intramuscularly, starting at a dose of 100 000-500 000 microbial bodies (at an individual dose for each patient) at intervals of 2-5 days. The course of vaccine therapy consists of 8-10 injections Brucellosis Treatment Guidelines A six-week regimen of co-trimoxazole and rifampicin is a popular treatment for children under 8 years old ( x ). For children 8 years old and older, doctors usually prescribe twice-daily regimens of doxycycline for six weeks, and they treat adults with a twice-daily regimen of a larger dose of the same drug for.

Brucellosis in children: Prevention, diagnosis and

CONCLUSION: Childhood brucellosis remains an important public health problem in central Greece. It usually occurs in families that raise small ruminants and the development of symptomatic infection in more than one family member is common. It may cause serious complications in children and treatment with at least two antibiotics for not less. Brucellosis is a systemic infectious disease transmitted from certain animals to humans (zoonotic disease). Brucellosis in humans is predominantly caused by four different species of Brucella bacteria: Brucella melitensis (goats, sheep, camels), Brucella suis (pigs), Brucella abortus (cows, buffalo, elk, camels, yaks), and Brucella canis (dogs).; Though all of these species can cause human. Patients with brucellosis were considered to have been treated if they received therapy with cotrimoxazole, rifampin, or a tetracycline for at least 4 weeks Brucellosis is a zoonotic infection caused by the bacterial genus Brucella. The bacteria are transmitted from animals to humans by ingestion through infected food products, direct contact with an infected animal, or inhalation of aerosols

Treatment of human brucellosis - PubMe

  1. 1. J Pediatr. 1982 Nov;101(5):725-7. Brucella canis infection in a 17-month-old child successfully treated with moxalactam. Tosi MF, Nelson TJ
  2. Treatment of childhood brucellosis with co-trimoxazole + rifampicin or doxycycline + rifampicin, according to patient age, is effective and has low relapse rates
  3. 5.6 Treatment of brucellosis in children less than eight years of age.....39 5.7 Post-exposure prophylaxis.....40 5.8 Vaccines and immune system stimulants..40 Î Key points on treatment of brucellosis in.
  4. a child concurrently infected with B. canis and cytomegalovirus, and resolved with antibiotic treatment for brucellosis. Serious syndromes including endocarditis have been reported in a few cases. B canis was associated with aortic valve vegetations and lower extremity aneurysms i
  5. Another dual therapies of brucellosis are known, for example doxycycline and gentamicin (DG) with the average failure rate of 5.2% and the relapse rate of 5.9%, or cotrimoxazole and rifampicin (RCTM) used in children brucellosis with the failure of treatment and relapse rates at 0-16.4% and 3.1-10%, respectively

Brucellosis Treatment & Management: Approach

The main Brucella spp. known to cause human disease are Brucella abortus (including the livestock vaccine strain Brucella abortus RB51), B. melitensis, B. suis, and B. canis. TRANSMISSION. Brucellosis is a classical bacterial zoonosis since animals are the only source of infection Brucellosis is an infectious disease caused by bacteria termed Brucella; the disease is found mainly in animals (zoonotic infection), but humans can be infected with these bacteria.; Brucellosis has been described as long as 2,000 years ago, and the organisms finally were identified in 1887; the disease is worldwide and usually confined to animals Issa H, Jamal M (1999) Brucellosis in children in south Jordan. East Mediterr Health J 5: 895-902. View Article Google Scholar 50. Tanir G, Tufekci SB, Tuygun N (2009) Presentation, complications, and treatment outcome of brucellosis in Turkish children. Pediatr Int 51: 114-119 Brucellosis (also known as 'undulant fever,' 'Mediterranean fever,' or 'Malta fever') is a zoonotic infection transmitted to humans from infected animals (cattle, sheep, goats, camels, pigs, or other animals) by ingestion of food products (such as unpasteurized dairy products) or by contact with tissue or fluids

Brucellosis - Clinical guideline

  1. Unresolved issues remain surrounding the treatment of human brucellosis. The present work aims to provide useful information to help clinicians make decisions when treating brucellosis patients. Information based on scientific evidence from clinical trials published over the past 30 years has been compiled and presented in an updated form, covering both focal and non-focal, or uncomplicated.
  2. for the treatment of brucellosis in adults and children over 8 years old [5—8]. It is well known that brucellosis treatment with a single agent or treatment for less than 4—6 weeks can result in relapses and complications [9]. Relapses are identified by a new positive blood culture or the appearance of signs or symptoms of brucellosis. Th
  3. However, the child did not respond to the treatment. Based on the histopathology and local endemicity, Brucella was suspected, and confirmed after serological testing. The child subsequently responded to treatment and, at latest follow-up at 1 year, had a full painless range of motion, with no relapse
  4. Less commonly, brucellosis can present with epididymo-orchitis, spondylodiscitis, neurobrucellosis, and endocarditis in adults or children. 1 According to the CDC, the disease course can last several weeks to months and requires antibiotic treatment for 6-8 weeks to prevent recurrence
  5. Brucellosis, a zoonotic disease of global importance [], is endemic in Saudi Arabia (national seroprevalence, 15%) [].Endemicity in this region results from the persistence of domestic animal reservoirs for Brucella species and the human consumption of unpasteurized dairy products [3, 4].. Various Brucella species are well-known causes of contagious abortion in cattle, sheep, goats, swine, and.
  6. Methods A total of 174 children diagnosed with brucellosis were included in the study. Data about demographic characteristics of patients, clinical and laboratory findings including Brucellacapt and RBT results, therapeutic approach, and response to treatment were collected from medical records
  7. This guidance covers treatment regimens of suspected or confirmed clinical cases of brucellosis. Although recommendations are also given for post exposure prophylaxis in case of suspected or confirmed exposure to brucella, there is little evidence to support its utility. Recommendations are compiled from references 1-4

Brucellosis - Diagnosis and treatment - Mayo Clini

  1. ation, blood transfusion, or by the use of conta
  2. Brucellosis: Importance Brucella canis Contagious Abortion, Undulant Fever Last Updated: May 2018 Brucellosis is a zoonotic bacterial disease caused by several species in the genus Brucella. Brucella canis is an important cause of reproductive failure in dogs, especially in kennels
  3. Brucellosis is the most common zoonotic infection in the world. Several antibiotics, separately or in combination, have been tried for treatment of human brucellosis. The inconsistencies between different treatment regimens warrants the need for a systematic review to inform clinical practice and future research
  4. Therapeutic Treatment: The recommended treatment in adults for brucellosis is doxycycline or doxycycline plus rifampin for 6 weeks. In children under 8 years of age, trimethoprim-sulfamethoxazole is substituted for doxycycline. Prophylactic Treatment: For cases of accidental inoculation or exposure, doxycycline an
  5. ated air, and co
  6. Human brucellosis is endemic in China and commonly occurs through contact with infected animals from working with livestock or consumption of unpasteurized dairy products. Although rare, human-to-human, and possible sexual transmission, of Brucella has been reported. In this report, we describe a case of likely mother-to-child transmission of Brucella in Hunan Province, China

Brucellosis: Symptoms and Treatmen

The child was started on intravenous gentamycin for 7 days and oral doxycycline and rifampicin, which were continued for 8 weeks. The child responded to the treatment and, at the latest follow-up at 1 year, was asymptomatic and had painless full range of motion of the involved hip. DISCUSSION Brucella is among the most common zoonotic diseases. Brucellosis is an important infectious disease especially endemic in Eastern and Southeastern Turkey. In this study, we aimed to evaluate the clinical, laboratory and treatment results of Brucellosis in children. Children with nonspecific findings suggestive of Brucellosis were included from September 2010 to February 2011 from the outpatient.

Background: Brucellosis constitutes a public health problem in Turkey. In endemic Brucella melitensis areas such as Turkey, children represent 20-25% of cases.. Methods: Hospital records of 90 children with brucellosis admitted during a 9 year period, 1997-2006, were evaluated retrospectively. Results: Of 90 patients, 27 (30%) were female and 63 (70%) were male (P < 0.05) Brucella spp. are the cause of brucellosis, which is a zoonosis transmitted by ingesting contaminated food (such as unpasteurized milk products), direct contact with an infected animal, or inhalation of aerosols. Transmission from human to human, for example through sexual intercourse or from mother to child, is exceedingly rare, but possible

Brucellosis is a common disease in the Arabian Peninsula and Mediterranean countries. Nervous system involvement, known as neurobrucellosis, should always be suspected in these endemic areas and can be confirmed by raised Brucella titers in the CSF. The outcome is favorable if treatment is started early and continued for an adequate period (1. The combination of tetracyclines and either an aminoglycoside or rifampin is effective in the treatment of brucellosis in humans; however, relapse remains a significant problem [].Moreover, for patients for whom tetracycline is contraindicated (i.e., pregnant women and children <8 years old), no other antibiotic offers a consistent treatment option that is as effective as doxycycline in the. Brucellosis Definition: Brucellosis is a disease caused by Brucella bacteria.Because Brucella can be airborne and weaponized, it is considered a bioterrorism agent. Brucella can infect humans and several types of animals. Signs and symptoms: Initial symptoms of brucellosis may include fever, sweats, malaise, anorexia, headache, myalgias, arthralgias

Transmission Brucellosis CD

Use: For the treatment of brucellosis due to Brucella species. Usual Adult Dose for Cholera. IV:-Initial dose: 200 mg IV on the first day, given in 1 or 2 infusions-Maintenance dose: 100 to 200 mg/day IV ORAL: Most Products:-Initial dose: 200 mg orally on the first day, given in 2 divided doses (100 mg every 12 hours What is the Treatment of Brucella Disease? It is known that the treatment method of Brucella disease is antibiotics. In general, these diseases are eliminated with antibiotics. Medications prescribed for treatments should be used for a period of 1 and a half months. Since it is a treatment-resistant disease, the probability of recurrence is high Treatment of Brucellosis in adults and children >8 yrs of age consists of doxycycline ( 200 mg/day) for 6 weeks in combination with an aminoglycoside -streptomycin,1 g/day intramuscularly for two to three weeks or gentamicin 5 mg/kg/day intravenously or intramuscularly for 7 to 10 days Brucella are extremely efficient in crossing the human skin barrier through cuts or breaks in the skin. Symptoms and treatment of brucellosis. The incubation period of Brucella—the time from exposure to the bacteria to the start of symptoms—is typically about three weeks. The primary complaints are weakness and fatigue

310-825-2631. Search. Children without a history of brucellosis and treatment for brucellosis and having typical signs of infection (fever, sweating, fatigue, and musculoskeletal pain) were included. Of 258 children, one hundred and eighty-six elementary school children met the inclusion criteria

Brucellosis,• Brucellosis, also called Bangs disease, Crimean fever, Gibraltar fever, Malta fever, Maltese fever, Mediterranean fever, rock fever, or undulant fever, is a highly contagious zoonosis caused by ingestion of unsterilized milk or meat from infected animals or close contact with their secretions. Dr.T.V.Rao MD 3 Nichols, E. Meningo-encephalitits due to brucellosis with the report of a case in whichBrucella abortus was from the cerebrospinal fluid, and a review of the literature. Ann. Inter. Med. 35 (1951) 673-693. Google Scholar 12. Ayala-Gaytän, J. J., Ortegön-Baqueiro, H., De la Maza, M. Brucella melitensis cerebellar abscess. J Herbal Treatment For Brucellosis 1. Take one tablespoon of Coconut Oil ( or any other carrier oil ) and add four drops of Fennel and two drops of Sandalwood Essential Oil in it. Mix them well. Add this blend to a warm bathtub and soak in it for 15 minutes. Repeat the process once a day Brucella arthritis in children. Infection. 1986; 14(5):233-6 (ISSN: 0300-8126) Lubani M; Sharda D; Helin I. A study in 50 children suffering from acute brucellosis demonstrated that acute arthritis is a common and often predominant manifestation of the disease Elimination of Brucella suis from feral pigs is unlikely. New, non-imported, human cases of brucellosis with no history of exposure to feral pigs should be reported to Biosecurity Queensland so that appropriate investigation and control measures, if required, can occur. Community Outbreaks/Epidemics Trace source of infection

Brucellosis Symptoms, Treatment, Diagnosis & Transmissio

Brucellosis is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions. It is also known as undulant fever, Malta fever, and Mediterranean fever.. Brucella species are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped (coccobacilli) bacteria.They function as facultative intracellular. Brucellosis initially causes a flu-like illness with fever, chills, headache, fatigue, and pain in the muscles, joints, or back. The fever might go up and down over a 24-hour period (another name for brucellosis is 'undulant fever'). Other symptoms can include loss of appetite and weight loss. Brucellosis can also cause long-lasting. Brucellosis is a zoonotic disease caused by brucella. It has been an increasing trend in recent years (Wang H, Xu WM, Zhu KJ, Zhu SJ, Zhang HF, Wang J, Yang Y, Shao FY, Jiang NM, Tao ZY, Jin HY, Tang Y, Huo LL, Dong F, Li ZJ, Ding H, Liu ZG, Emerg Microbes Infect 9:889-99, 2020). Brucellosis is capable to invade multiple systems throughout the body, lacking in typical clinical manifestations. Brucelosis Se denomina Brucelosis, a la infección causada por bacterias del género Brucella. También es llamada, fiebre ondulante, fiebre mellitiensis o de Malta, fiebre de Traum, fiebre caprina, fiebre de Chipre, fiebre de Bang, fiebre de Gibraltar, o fiebre sudoralis . 3

This test looks at fluid from your spinal cord to find out if you have an illness called brucellosis Brucella PCR can also remain positive despite successful treatment, and therefore needs to be correlated clinically. Neurobrucellosis This is a very rare condition in the UK Use: Treatment of asymptomatic carriers of N meningitidis to eliminate meningococci from the nasopharynx. Usual Pediatric Dose for Tuberculosis - Latent. US CDC Recommendations: Children: 10 to 20 mg/kg IV OR orally once a day with/without isoniazid Maximum dose: 600 mg/day Duration of therapy: 4 month

What is the treatment? Brucellosis can be treated with antibiotics, but treatment can be difficult. Doctors may prescribe a combination therapy to prevent reoccurring infection. All antibiotics should be taken exactly as child is unwilling or unable to participate in activities. They should also be excluded if the staf Brucellosis has always been an unusual disease in children and, concomitant with the control of the disease in domestic animals, reports have become sparse. The pediatrician, therefore, may not be aware of the protean clinical manifestations of childhood brucellosis. In 1973, nine cases occurred during a three-month period in El Paso, Texas. All cases were marked by spiking fevers and lethargy.

  1. Untreated brucellosis can last from several weeks to several years (5). Osteoarticular involvement is the most common complication seen in up to half of brucellosis cases (6). Rare complications in the course of brucellosis may involve the respiratory system (7). Neurological complications may also occur with frequent sequelae, despite treatment
  2. Brucellosis is a classical bacterial zoonosis since animals are the only source of infection. Humans most commonly acquire the infection through consumption of unpasteurized dairy products (such as raw milk, soft cheese, butter, and ice cream). The bacteria can also enter the body via skin wounds, mucous membranes, or inhalation, so direct.
  3. Brucellosis is caused by Brucella species, which are gram-negative bacteria. Symptoms begin as an acute febrile illness with few or no localized signs and may progress to a chronic stage with relapses of fever, weakness, sweats, and vague aches and pains. Diagnosis is by culture, usually from the blood

Brucellosis (Brucella species) Brucellosis is a disease caused by coccobacilli from the genus Brucella . It's usually found in animals, such as sheep, cattle, and goats When brucella is suspected, such as in patients with high epidemiologic risk, blood cultures should be incubated for up to 2 weeks and Brucella serologic testing should be performed. Outside the United States, the Coombs test is commonly used for the diagnosis of brucellar NVO [51]; in one study, a titer of ≥1:160 was found in all patients. The treatment process lasts for months, although this disease may relapse. Brucellosis is pretty rare in the United States although it is present in significant numbers elsewhere across the globe. Avoiding unpasteurized dairy products and wearing protective clothing while near animals can prevent an individual from contracting Brucellosis Brucellosis is an infection caused by several species of the gram-negative bacteria Brucella and characterized by fever and bodywide symptoms. Brucellosis is acquired mainly by having contact with infected animals or by consuming unpasteurized contaminated milk or other dairy products or undercooked contaminated meat


A case of acute septic arthritis hip caused by Brucella

The presented case was part of a retrospective cohort study that aimed to describe the clinical presentations and treatment strategies of brucellosis among Saudi children . Conclusions Neurobrucellosis should be considered as a differential diagnosis for unexplained neurological symptoms, particularly in endemic countries such as Saudi Arabia Home | SA Healt

However, lung involvement is extremely rare in the course of childhood brucellosis. This case report describes a 6-year-old child who was referred to our hospital as meningococcemia but diagnosed as lobar pneumonia in follow-up. Brucella agglutination test and bone marrow culture were diagnostic of brucellosis. The patient responded to the. Brucella suis was the first pathogenic organism used by the U.S. military as a weapon backing in the 1950s. Although treatment is available for brucellosis, it is prolonged antibiotic therapy. In addition, early diagnosis is problematic and no acceptable vaccines have been made (Paulsen et al. 2002). Genome Structur 2] Neisseria meningitidis. > Pasteurella multocida. Brucella species : non-motile, non-encapsulated coccobacilli, which function as facultative intracellular parasites. Cause of brucellosis, which is transmitted by ingesting contaminated food (such as unpasteurized milk products), direct contact with an infected animal, or inhalation of aerosols

If Brucella canis is diagnosed, determine possible exposure of patient. Dogs are the primary reservoir. Brucellosis is more common in stray or population-housed dogs, but pet dogs can also carry the disease. Routine testing can be performed by a veterinarian. Note that there is no antibiotic treatment regimen for dogs that guarantees eliminatio Canine Brucellosis: Facts for Dog Owners Canine Brucellosis Canine brucellosis is an infectious disease caused by the bacteria Brucella canis. There are other species of Brucella that affect different animals, and a few of these can also infect dogs, but B. canis is the most common Brucella species found in infected dogs Brucellosis is a neglected zoonosis. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. Over the past two decades, improvements have been made to better understand the various aspects of human and animal brucellosis. Meanwhile, especially in the developing world, immense challenges that.

Brucellosis is one of the world's most widespread zoonoses which is highly infective for humans. Human brucellosis usually presents as an acute febrile illness, but the disease may persist as relapse, chronic localized infection or delayed convalescence. Most cases are caused by Brucella melitensis and all age groups are affected Canine brucellosis is an infectious and zoonotic disease caused by Brucella canis, which has been reported worldwide, and is a major public health concern due to close contact between dogs and humans. In dogs, canine brucellosis manifests with abortion outbreaks, reproductive failure, enlargement of lymph nodes, and occasionally affects the osteoarticular system, although the occurrence of. Canine brucellosis is an infectious disease caused by the . Brucella canis (B. canis) bacterium. B. canis . is the Treatment: treatment is not recommended. If owners choose to pursue treatment it is important to young children and pregnant women may be at higher risk of severe disease if they acquire the infection. Althoug

Brucellosis. Brucella are small parasites that can cause acute and chronic disease in both animals and humans. Brucella suis is endemic in Florida's wild hogs. Feral swine herds in central Florida, where most of the human cases are reported, have an infection rate of about 50%. The rest of the state's hogs have a seroprevalence rate of 10-20% Canine brucellosis is an infectious disease caused by the Brucella bacteria. The illness in dogs is caused by Brucella canis (B. canis). However, Brucella organisms commonly associated with other animal species, such as Brucella suis (pigs) and Brucella abortus (cattle and bison), can infect dogs depending upon their exposures to these species This test looks for brucellosis, an infectious disease usually caused by handling animals or milk products infected with the brucella bacteria. Brucella Antibody Skip to topic navigatio The effectiveness of treatment of human brucellosis caused by Brucella melitensis with ciprofloxacin alone was investigated in a prospective nonrandomized study. Subjects with central nervous system involvement, endocarditis, or severe renal dysfunction; children under 16 years of age; and pregnant women were excluded from the study. Of 19 patients, 16 completed the study; 7 were diagnosed as. Previous studies showed that soluble IL-2Rα is an important marker of cellular immune activation and might be a marker of treatment efficacy for children with brucellosis. However, data regarding adult patients with brucellosis were unknown. The aim of study was to explore the potential role of serum sIL-2Rα evaluating treatment responses in adult patients with brucellosis, and T cell immune.

Brucellosis is considered a zoonotic disease which is still an important health problem in endemic areas such as the Middle East, the Mediterranean, and Asia. Brucellosis is a systemic infection that might affect any organ or system in the body. Ocular involvement has been reported in 21% of brucellosis patients. The most common ocular manifestations of brucellosis were considered as anterior. Brucellosis may be complicated by infection of the joints or spine or involvement of the heart, eyes, kidneys, or lungs. Brucella spondylitis is an arthritis of the spine that generally occurs several weeks after initial infection with brucellae and may involve any part of the spine, although the lumbar region is the most commonly affected site Brucellosis is an infectious disease usually caused by handling animals or milk products infected with the brucella bacteria. If you have brucellosis, your body will make certain antibodies to fight the brucella bacteria. This test looks for those antibodies in your blood. The brucella bacteria can infect dogs and livestock, including cows. Brucellosis is a worldwide zoonosis, with the Mediterranean basin, the Middle East, India, Mexico, and Central and South America being the most affected areas [].The disease has generalized and systemic symptoms, and almost every organ of the human body can be affected by Brucella.Despite this, the incidence of cardiovascular complications in brucellosis, such as endocarditis, myocarditis or. According to the brucellosis treatment standards issued by the National Health Commission in 2019, brucellosis should be diagnosed through epidemiological contact tracing, clinical manifestations.

Ocular manifestations in a child with systemic brucellosi

Streptococcus pyogenes (Group A Streptococcus) on ChromID

(PDF) Brucellosis in children: Prevention, diagnosis and

Il lupo grigio (Canis lupus Linnaeus, 1758), detto anche lupo comune o semplicemente lupo, è un canide lupino, presente nelle zone remote del Nordamerica e dell'Eurasia. È il più grande della sua famiglia, con un peso medio di 43- 45 kg per i maschi, e 36-38,5 kg per le femmine

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