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Age related diseases slideshare

AGING-RELATED CHANGES Although the immune system deteriorates with age, called immune-senescence, a major hallmark of aging is an increase in inflammation levels, reflected in higher levels of circulating pro-inflammatory cytokines and that may contribute to several age-related disorders such as Alzheimer's disease, atherosclerosis and. Age-Related Macular Degeneration Dr Charlotte Hazel Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website Disease presentation in elderly 1. Disease Presentation in Elderly Dr. DoHA RASHEEDY ALY Assistant Professor of Geriatric Medicine Department of Geriatric and Gerontology Ain Shams University 2. Early detection Good prognosis 2/25/2018 2 3. Think about altered presentation 2/25/2018 3 4

Aging-related Changes - SlideShar

• Age-related macular degeneration has recently been named by Professor A C Bird and coworkers who performed the International ARM Epidemiological study group. • The disorder is either referred to age related maculopathy (ARM) or age-related macular degeneration (AMD). 5 AGEING It is a progressive and generalized impairment of body functions resulting in, loss of adaptive responses to stress and increasing the risk of age-related diseases. People more than 60 yrs are considered elderly. Old age is not a disease but a normal and inevitable biological phenomenon. 7 Factors Refractive Changes Age Related Diseases Decreased retinal luminance Increased light scattering Aging neural elements 21. Refractive Changes In the normal eye free from cataract and diabetes Refractive change is hypermetropia at a rate of little more than 0.25D per decade after 40 Due to increase in axial thickness of lens and flattening. Age-Related Eye Disease Study (AREDS) special vitamins/min erals supplement formulation. Laser surgery. Eye injections. Photodynamic therap y. (continued from previous slide) AMD.

Age-Related Macular Degeneration - SlideShar

• Disease: Diseases affecting enamel and dentin can lead to tooth discoloration. Certain infections in pregnant mothers can cause tooth discoloration in the baby by affecting enamel development. • Ageing: As you age, the outer layer of enamel on your teeth wears away, revealing the dentin's natural, yellow colour 1. Chronic health conditions. According to the National Council on Aging, about 92 percent of seniors have at least one chronic disease and 77 percent have at least two. Heart disease, stroke, cancer, and diabetes are among the most common and costly chronic health conditions causing two-thirds of deaths each year

Neurological Disorders - a Common Problem of Aging. As we age, all of us notice changes in our hair, skin and joints that let us know we are getting older. Along with these visible changes, our brains and central nervous system are going through the aging process too. This is one reason you are more likely to suffer from a neurological. 4. Stomach. Altered gastric microbiota, reduced mucosal protective mechanisms, decreased gastric blood flow, and consequently compromised repair mechanisms are the hallmarks of age-related gastric changes [40, 41].These changes make older people more susceptible to the development of several diseases, such as gastric ulcer, atrophic gastritis, and peptic ulcer disease [] Age-related macular degeneration (AMD) is an eye disease that can blur the sharp, central vision you need for activities like reading and driving. Age-related means that it often happens in older people. Macular means it affects a part of your eye called the macula. AMD is a common condition — it's a leading cause of vision loss. Some diseases of the circulatory system, such as stroke, can cause dizziness and other balance problems. Low blood pressure can also cause dizziness. Head injury and many medicines may also lead to balance problems. Check with your doctor if you notice a problem while taking a medication. Ask if other medications can be used instead

Disease presentation in elderly - SlideShar

Common health conditions associated with ageing. Common conditions in older age include hearing loss, cataracts and refractive errors, back and neck pain and osteoarthritis, chronic obstructive pulmonary disease, diabetes, depression, and dementia. Furthermore, as people age, they are more likely to experience several conditions at the same time Hearing loss is a common problem caused by noise, aging, disease, and heredity. People with hearing loss may find it hard to have conversations with friends and family. They may also have trouble understanding a doctor's advice, responding to warnings, and hearing doorbells and alarms. Approximately one in three people between the ages of 65. What is a genetic disease or disorder? Learn from a list of genetic diseases that are caused by abnormalities in an individual's genome. There are four main types of genetic inheritance, single, multifactorial, chromosome abnormalities, and mitochondrial inheritance. Genetic testing is available for some genetic diseases Even without the presence of disease, a person's body will undergo changes in it's structure and function[1]. Aging is an independent risk factor for cardiovascular disease. The effects of aging are widely diverse and can be identified at the molecular, cellular, tissue, organ, and system levels as contributing to the altered function of the cardiovascular system Contribution of senescence to age-related diseases Now that a general causative role for senescence during aging has been established, the next step is to identify how senescence contributes to different age-related pathologies such as glaucoma ( Liton et al., 2005 ) or osteoarthitis ( Jeon et al., 2017 ; Fig. 4 )

Age related macular degeneration - SlideShar

  1. Fractures. Fractures are frequent in the elderly and result mainly from the effects of falls and osteoporosis.[3,4] Low-impact falls, even from standing height, are the most common cause of injury in geriatric patients.[] Falling is a multi-factorial problem due to both extrinsic (e.g., environmental and housing conditions) and intrinsic risk factors (e.g., impaired mobility, loss of muscular.
  2. Rheumatoid arthritis is an autoimmune disease. Normally, your immune system helps protect your body from infection and disease. In rheumatoid arthritis, your immune system attacks healthy tissue in your joints. It can also cause medical problems with your heart, lungs, nerves, eyes and skin
  3. Laron syndrome is caused by changes (mutations) in the GHR gene.This gene encodes growth hormone receptor, which is a protein found on the outer membrane of cells throughout the body. Growth hormone receptor is designed to recognize and bind growth hormone, which triggers cellular growth and division
  4. Observational findings achieved during the past two decades suggest that the intestinal microbiota may contribute to the metabolic health of the human host and, when aberrant, to the pathogenesis of various common metabolic disorders including obesity, type 2 diabetes, non-alcoholic liver disease, c
  5. Mitral annulus calcification (MAC) is a chronic, degenerative process in the fibrous base of the mitral valve. Although MAC was initially thought to be an age-related degenerative process, there is accumulating evidence that other mechanisms, such as atherosclerosis and abnormal calcium-phosphorus metabolism, also contribute to the development of MAC
  6. We are open for safe in-person care. Learn more: Mayo Clinic facts about coronavirus disease 2019 (COVID-19) Our COVID-19 patient and visitor guidelines, plus trusted health information Latest on COVID-19 vaccination by site: Arizona patient vaccination updates Arizona, Florida patient vaccination updates Florida, Rochester patient vaccination updates Rochester and Mayo Clinic Health System.
  7. Alpha-1 antitrypsin deficiency is a genetic condition that puts people at risk for lung and liver disease. Alpha-1 antitrypsin is a protein produced by the body to protect various organs from.

Anti-integrin therapies show potential in treating retinal diseases. Anti-integrin agents tackle the multi-factorial nature of diabetic retinopathy (DR) and AMD and show promise as injectable and topical agents in preclinical and early clinical studies. Integrin inhibition has potential to serve as Age-related macular degeneration (AMD) is a representative retinal diseases associated with the loss of RPECs. AMD is a leading cause of central vision loss in the western world. A gradual, age-dependent decline in function and viability of RPE cells, combined with lipofuscin accumulation, leads to AMD : Fundus autofluorescence (FAF) provides detailed insight into the health of the retinal pigment epithelium (RPE). This is highly valuable in age-related macular degeneration (AMD) as RPE damage is a hallmark of the disease. The purpose of this paper is to critically appraise current clinical descri

Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Manual was first published in 1899 as a service to the community Resources with information on diseases and conditions for parents with children ages 4-11. The links on this page will help you learn about diseases and conditions that could affect your child. Skip directly to site content Skip directly to page options Skip directly to A-Z link Significance Persons > 65 years of age compose only about 12% of the US population 1/3 (33%) of all drugs are prescribed for them Consume more than 50% of over-the-counter medicines as well. More than 80% of all older people take at least one medication daily. Pharmacokinetics: study of the action of a dru Aging changes in immunity. Your immune system helps protect your body from foreign or harmful substances. Examples are bacteria, viruses, toxins, cancer cells, and blood or tissues from another person. The immune system makes cells and antibodies that destroy these harmful substances. As you grow older, your immune system does not work as well.

Lewy body disease (several others) Other NCDs . Neurocognitive Disorders of the DSM-5 . Neurocognitive Disorders of the DSM-5 Delirium Traumatic Brain Injury Maya Yutsis, PhD Clinical Neuropsychologist Polytrauma Transitional Rehabilitation Program VA Palo Alto Health Care System AGING CHANGES. Heart: The heart has a natural pacemaker system that controls the heartbeat. Some of the pathways of this system may develop fibrous tissue and fat deposits. The natural pacemaker (the sinoatrial or SA node) loses some of its cells. These changes may result in a slightly slower heart rate multiple age-related diseases by targeting the aging process. Aging hallmarks can be divided into three categories: (1) primary, or the causes of age-associated damage; (2) an-tagonistic, or the responses to the damage; and (3) integrative, or the consequences of the responses and culprits of the aging phenotype Many diseases of the colon and rectum can be prevented or minimized by maintaining a healthy lifestyle, practicing good bowel habits and getting screened for cancer. A colonoscopy is recommended for average-risk patients at age 45. If you have a family history of colorectal cancer or polyps, a colonoscopy may be recommended at a younger age Urinary diseases can affect men, women, and children of every age. Urinary diseases affect specific parts of the body. In females they involve the urinary tract, in men, it affects the reproductive organs as well. Here are some common types of urinary diseases. Some most common urinary diseases. There are plenty of urinary disorders

Overview What is Addison's disease? Addison's disease is a disorder in which the adrenal glands - which sit on top of the kidneys - do not produce enough of the hormones cortisol and aldosterone. (Hormones are chemicals that control the function of tissues or organs.) Cortisol helps the body respond to stress, including the stress of illness, injury, or surgery Appropriate photographs, diagrams and other visuals for each slide · Name of the disease or disorder · A basic description of the disease or disorder · Identify and explain how it affects one major body system · How the disease or disorder affects additional body systems · Causes of the disease or disorder- How can a person get it Older persons who were free from specific visual pathologies exhibited an age-related decline in presenting far acuity as did those with documented visual pathologies. Despite the demonstrated loss in acuity with age, the majority of persons maintain at least fair acuity (20/40 or better) into their 80's

1 Kidney Disease Center, The 1st Affiliated Hospital of Zhe Jiang University, Zhejiang, China. PMID: 17943234 DOI: 10.1007/s00391-007-0480- Abstract Telomeres form the ends of human chromosomes. Telomeres shorten with each round of cell division and this mechanism limits proliferation of human cells to a finite number of cell divisions by. A three-pronged health challenge is putting the squeeze on already-scarce resources in the developing world, with heart disease, diabetes, and other chronic ailments growing. At the same time, the threat from infectious diseases and neglected tropical diseases demands new attention, the head of the Institute of Medicine said Monday (Nov. 8)

Geriatric care - SlideShar

Meniere's disease is a disorder of the inner ear that can lead to dizzy spells (vertigo) and hearing loss. In most cases, Meniere's disease affects only one ear. Meniere's disease can occur at any age, but it usually starts between young and middle-aged adulthood. It's considered a chronic condition, but various treatments can help relieve. Heart valve disease. Symptoms and causes. Bicuspid aortic valve. With this birth defect, the aortic valve has only 2 leaflets instead of 3. If the valve becomes narrowed, it is harder for the blood to flow through, and often the blood leaks backward This heart disease prediction model with an accuracy of 90.32% will help people especially medical professionals to scale different scenarios. They will have a good understanding of a person's health and they can easily understand age related health risk and thus they can warn a patient beforehand Common eye problems include. Refractive errors. Cataracts - clouded lenses. Optic nerve disorders, including glaucoma. Retinal disorders - problems with the nerve layer at the back of the eye. Macular degeneration - a disease that destroys sharp, central vision. Diabetic eye problems. Conjunctivitis - an infection also known as pink eye

Changes of visual function with age

Huntington disease (HD) is an inherited condition that causes progressive degeneration of neurons in the brain. Signs and symptoms usually develop between ages 35 to 44 years and may include uncontrolled movements, loss of intellectual abilities, and various emotional and psychiatric problems A dark shadow or curtain on the sides or in the middle of your field of vision. Retinal detachment is a medical emergency. If you have symptoms of a detached retina, it's important to go to your eye doctor or the emergency room right away. The symptoms of retinal detachment often come on quickly. If the retinal detachment isn't. PPT - Introduction: Low-grade chronic inflammation plays a major role to the disease pathogenesis in dry age related macular degeneration (AMD). Currently there is no treatment to stop progression or improve vision in these patients. PowerPoint presentation | free to download - id: 76cf22-Njk4N. The Adobe Flash plugin is needed to view this.

Age-related conditions. There is a wide range of skin diseases and they can affect people of all ages. In children. Share on Pinterest Measles mostly affects children and pregnant women,. diseases were the most common etiology, representing 63% of all cases of native heart valve disease. The rheumatic heart disease (RHD) came next, accounting for 22% of all patients [8]. This supports the understanding of a changing in the epidemiology of valvular diseases in the last 60 years, with a shift from rheumati ADVERTISEMENTS: Primary hypothyroidism or thyroid atrophy is the most common cause of hypothyroidism (other than iatrogenic ablation of thyroid) in adults. The disease is more common in women. Women of 40 to 60 years of age are often affected. There is asymptomatic or unrecognized thyroiditis with progressive destruction of the thyroid gland. In some cases, [

The common diseases and disorders associated with the female reproductive system are explained with respect to their organs as follows: Gynecologic Cancer. Gynecologic cancer refers to cancer that originates at any part of the female reproductive system. This group of cancer is widespread among women throughout the world Cervical spondylosis, commonly called arthritis of the neck, is the medical term for these age-related, wear-and-tear changes that occur over time. Cervical spondylosis is extremely common. More than 85 percent of people over the age of 60 are affected. The condition most often causes pain and stiffness in the neck—although many people with. A cataract is a cloudy area in the lens of your eye. Most cataracts happen because of normal changes in your eyes as you get older. But you can get cataracts for other reasons too. Read about the five main types: age-related cataract, traumatic cataract, radiation cataract, pediatric cataract, and secondary cataract

Aortic valve disease may be caused by a heart defect present at birth (congenital). It can also be caused by other conditions, including age-related changes to the heart, infections, high blood pressure or injury to the heart. Risk factors. Risk factors of aortic valve disease include: Older age Miller-Fisher syndrome is a rare, acquired nerve disease that is a variant of Guillain-Barré syndrome. It is characterized by abnormal muscle coordination with poor balance and clumsy walking, weakness or paralysis of the eye muscles, and absence of the tendon reflexes. Like GBS, symptoms may follow a viral illness Age-related eye disease. A six-year trial, the Age-Related Eye Disease Study (AREDS), found that a combination of vitamin C, vitamin E, beta-carotene, and zinc offered some protection against the development of advanced age-related macular degeneration, but not cataracts, in people who were at high risk of the disease. [16,17 Meniere's is an incurable disease influencing the inner ear. The disorder affects the flow of fluids which influence balance and hearing. A primary physician might suspect Meniere's based on your complaints, but most people receive the news from a referral to an Otolaryngologist (one who has experience with Meniere's)

Dental problem and treatment - SlideShar

You have chronic kidney disease, diabetes or coronary artery disease; Ask your doctor what your blood pressure treatment goal should be. Also, the ideal blood pressure treatment goal can vary with age and health conditions, particularly if you're older than age 65. Medications used to treat high blood pressure include: Diuretics Age-related macular degeneration (AMD) is an eye disease that destroys the macula, which is part of the retina at the back of your eye. Your macula allows you to see color, fine detail, and things. Coronary heart disease is a type of heart disease that happens when the arteries of the heart cannot deliver enough oxygen-rich blood to the heart. Learn about causes and symptoms of coronary heart disease, how it is treated, and NHLBI research The risk of developing an ERM increases with age, and persons with predisposing ocular conditions may develop ERM at an earlier age. The most common association, however, is PVD. Studies have shown that 2% of patients over age 50 and 20% over age 75 have evidence of ERMs, although most do not need treatment. Both sexes are equally affected

10 common elderly health issues - Vital Recor

Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast. A breast is made up of three main parts: lobules, ducts, and connective tissue Age-related disease is delayed by almost one decade. Age-related disease occurs at about the same time in centenarians as in individuals with related disease occurs at about the same time in centenarians as in individuals with average life expectancy. Age-related disease does not occur in centenarians. Age-related disease may occur at about the.

Pediatric abdominal pain

with multiple chronic health conditions and identifies the systems structures that, if developed, would facilitate improvements in care of people with multiple chronic health conditions. 39% Data source: Australian Bureau of Statistics.1 39% 25% 36% None One or two chronic conditions Three or more chronic conditions of Australian adults hav Because of these age-related changes, the brain may function slightly less well. Older people may react and do tasks somewhat more slowly, but given time, they do these things accurately. Some mental functions—such as vocabulary, short-term memory, the ability to learn new material, and the ability to recall words—may be subtly reduced. Age-related skin conditions: A number of changes occur in the skin with age, including thinning of the skin, loss of ability to retain water in the skin, and a loss of moisturizing glands in the skin, resulting in dryness, loss of immune cells in the skin resulting in decreased wound healing, and a loss of elasticity. Some of these effects can. Age-related histomorphometric changes in labial salivary glands with special reference to the acinar component. Experimental Gerontology, 35 (8) Age-dependent decreases in human submandibular gland flow rates as measured under resting and post-stimulation conditions. Journal of Dental Research, 64 (5) (1985), pp. 822-825

Causes. Numerous studies have been conducted to identify risk factors for development of senile cataracts. Various culprits have been implicated, including environmental conditions, systemic diseases, UV exposure, diet, and age. [ 14, 15] West and Valmadrid stated that age-related cataract is a multifactorial disease with different risk factors. Sebostasis is age related and has an occurrence of about 80% in older people. Mechanical or chemical degreasing, such as frequent washing or very dry hair, can also cause sebostasis. Clinical features of sebostasis. The clinical symptoms show a scaly, rough skin and the patient often experiences itching and an unpleasant tightness of the skin Neuromuscular disorders affect your neuromuscular system. They can cause problems with. The nerves that control your muscles. Your muscles. Communication between your nerves and muscles. These disorders can cause your muscles to become weak and waste away. You may also have symptoms such as spasms, twitching, and pain Chronic disease epidemics take decades to become fully established. Chronic diseases often begin in childhood. 24 Vision loss, age-related and other 14.1 25 Cirrhosis of the liver 13.9 Source: reference 68. 19 69, 70). The costs of asthma are high in severe or uncontrolled asthma (71)

Neurological Disorders - a Common Problem of Agin

Laron syndrome (LS), also known as growth hormone insensitivity is an autosomal recessive disorder characterized by a lack of insulin-like growth factor 1 (IGF-1; somatomedin) production in response to growth hormone (GH; hGH; somatotropin). It is usually caused by inherited growth hormone receptor (GHR) mutations.. Affected individuals classically present with short stature between −4 to. In high income countries, diseases such as glaucoma and age-related macular degeneration are more common. Among children, the causes of vision impairment vary considerably across countries. For example, in low-income countries congenital cataract is a leading cause, whereas in middle-income countries it is more likely to be retinopathy of. Degenerative nerve diseases affect many of your body's activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is unknown

Gastrointestinal Tract Disorders in Older Ag

THE ROLE OF ANTI-VEGF THERAPY IN RETINA DISEASES

Age-Related Macular Degeneration National Eye Institut

Aging changes in the female reproductive system result mainly from changing hormone levels. One clear sign of aging occurs when your menstrual periods stop permanently. This is known as menopause. The time before menopause is called perimenopause. It may begin several years before your last menstrual period The Age Related Eye Disease Study (AREDS) Group 52,53 reported the results from a large prospective double blind placebo controlled study across 11 centres in the USA. The supplements were of vitamin C (500 mg) plus vitamin E (400 IU) plus β carotene (15 mg), or zinc (80 mg) plus copper (2 mg), or both of these. 4629 patients were followed up. Spondylitis affects a number of people irrespective of age or gender. Besides the pain, stiffness, bony growths on the spine, pain in ligament and tendons, a person may suffer from other conditions like fatigue, fever, loss of appetite, redness of eyes Joint disease, any of the diseases or injuries that affect human joints. Diseases of the joints may be short-lived or chronic, painful or merely nagging and uncomfortable; they may be confined to one joint or may affect many parts of the skeleton. Learn more about the types of joint disease and their management Skin disorders vary greatly in symptoms and severity. They can be temporary or permanent, and may be painless or painful. Some have situational causes, while others may be genetic

Inflammatory bowel disease affects approximately 1.4 million Americans, and its peak onset is in persons 15 to 30 years of age. 18 Crohn's disease generally involves the ileum and colon, but it. If you're over 50, test for symptoms of age-related macular degeneration (AMD) at home with an Amsler grid. Amsler grids are available FREE from Macular Disease Foundation Australia. Macular Disease Foundation Australia provides information, guidance and support on prevention, early detection, treatment and living well with macular disease The Centers for Disease Control and Prevention (CDC) established an office in Nigeria in 2001. CDC works with federal and state ministries of health to address HIV, tuberculosis, malaria, and immunization for vaccine-preventable diseases as well as on strengthening laboratory, surveillance, and workforce capacity to respond to disease outbreaks Heart conditions and other disorders, age-related changes, rheumatic fever, or infections can cause acquired heart valve disease. These factors change the shape or flexibility of once-normal heart valves. The cause of congenital heart valve disease isn't known. It occurs before birth as the heart is forming

Immunosenescence journal club

Balance Problems and Disorders National Institute on Agin

Jaiswal S, Fontanillas P, Flannick J, et al. Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med. 2014;371(26):2488-2498. 12. Jaiswal S, Natarajan P, Silver AJ, et al. Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease. N Engl J Med. 2017;377(2):111-121. 13 Epidemiology and Risk Factors for Age-Related Macular Degeneration. Johanna M. Seddon, Lucia Sobrin, in Retina (Fifth Edition), 2013. Conclusion. AMD is a multifactorial disease that affects a large segment of the population and research to date has yielded some preventive measures and a few effective treatments for the advanced wet form of the. Neurodegenerative diseases affect millions of people worldwide. Alzheimer's disease and Parkinson's disease are the most common neurodegenerative diseases. In 2016, an estimated 5.4 million Americans were living with Alzheimer's disease. An estimated 930,000 people in the United States could be living with Parkinson's disease by 2020

Ageing and health - World Health Organizatio

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